Fig. 2

Forest plots of diagnostic accuracy measures for Abbott ARCHITECT HCV Ag assay using a bivariate random-effects model. This figure presents forest plots showing the diagnostic accuracy of the Abbott ARCHITECT HCV Ag assay for detecting active HCV infection in HCV/HBV coinfected individuals compared to a confirmatory nucleic acid test. Each panel shows (A) sensitivity, (B) specificity, (C) PLR, and (D) NLR with corresponding 95% CI. 95% CI 95% confidence interval; df degrees of freedom; HBV hepatitis B virus; HCV hepatitis C virus; I2 Higgins’ inconsistency index; NLR negative likelihood ratio; PLR positive likelihood ratio; Q Cochran’s Q test statistic; Se sensitivity; Sp specificity